PRODUCT NAME: Afatinib Impurity 37
Date of Mfg: Sample COA	RETEST DATE: Sample COA

Catalogue Number	AFI-041
Item/Batch Number	Sample COA
Quantity	Sample COA
CAS Number	2223677-61-8
Mol. Formula	C20H19ClFN5O2
Molecular Wt	415.9 g/mol
IUPAC	(E)-N-(4-((3-chloro-4-fluorophenyl)amino)-7-hydroxyquinazolin-6-yl)-4-(dimethylamino)but-2-enamide
Synonyms	2-Butenamide, N-[4-[(3-chloro-4-fluorophenyl)amino]-7-hydroxy-6-quinazolinyl]-4-(dimethylamino)-, (2E); (2E)-N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-hydroxy-6-quinazolinyl]-4-(dimethylamino)-2-butenamide
Long Term Storage Condition	-20°C to 4°C
Handling instruction	Sample COA

Test	Results
Appearance	solid powder
Water content by KF/TGA	Sample COA
% Potency = [100 - (Water content by KF)] X HPLC Purity)] / 100	Sample COA
Identification by HNMR	Sample COA
Identification By IR	Sample COA
Mass (ESI)	Sample COA
Solubility
Purity	NLT 98%
Analysis Date (Release Date)	Sample COA
Attachments	Sample COA
Other Information	Sample COA
Note: This material can be used as a referance standard and is for research purpose ONLY and not for human consumption