CERTIFICATE OF ANALYSIS

PRODUCT NAME: Encorafenib Nitroso Impurity
Date of Mfg: Sample COA RETEST DATE: Sample COA
Catalogue Number NIO-589
Item/Batch Number Sample COA
Quantity Sample COA
CAS Number NA
Mol. Formula C22H26ClFN8O5S
Molecular Wt 569.0
Synonyms Methyl (S)-(1-((4-(3-(5-chloro-2-fluoro-3-(methylsulfonamido)phenyl)-1-isopropyl-1H-pyrazol-4-yl)pyrimidin-2-yl)(nitroso)amino)propan-2-yl)carbamate
Long Term Storage Condition Keep container tightly closed in a dry and well-ventilated place
Handling instruction Sample COA
Test Results
Appearance
Water content by KF/TGA Sample COA
% Potency = [100 - (Water content by KF)] X HPLC Purity)] / 100 Sample COA
Identification by HNMR Sample COA
Identification By IR Sample COA
Mass (ESI) Sample COA
Solubility
Purity NLT 98%
Analysis Date (Release Date) Sample COA
Attachments Sample COA
Other Information Sample COA
Note: This material can be used as a referance standard and is for research purpose ONLY and not for human consumption
This is Sample COA