PRODUCT NAME: Encorafenib Nitroso Impurity
Date of Mfg: Sample COA	RETEST DATE: Sample COA

Catalogue Number	NIO-589
Lot Number	Sample COA
Batch Quantity	Sample COA
CAS Number	NA
Mol. Formula	C22H26ClFN8O5S
Molecular Wt	569.0
Long Term Storage Condition	Keep container tightly closed in a dry and well-ventilated place	Handling instruction	Sample COA
Chemical Name	Encorafenib Nitroso Impurity
Synonyms	Methyl (S)-(1-((4-(3-(5-chloro-2-fluoro-3-(methylsulfonamido)phenyl)-1-isopropyl-1H-pyrazol-4-yl)pyrimidin-2-yl)(nitroso)amino)propan-2-yl)carbamate

Test	Results
Appearance
Identification by 1H NMR	Sample COA
Identification By IR	Sample COA
Mass (ESI)	Sample COA
Purity	NLT 98%
Wt. Loss by TGA	Sample COA
% Potency	Sample COA
Solubility
QC Release Date	Sample COA
Attachments	Sample COA
Note: This material can be used as a referance standard and is for research purpose ONLY and not for human consumption