PRODUCT NAME: Acalabrutinib Impurity 18
Date of Mfg: Sample COA	RETEST DATE: Sample COA

Catalogue Number	ATB-032
Item/Batch Number	Sample COA
Quantity	Sample COA
CAS Number	1148-11-4
Mol. Formula	C13H15NO4
Molecular Wt	249.32 g/mol
IUPAC	((Benzyloxy)carbonyl)-L-proline
Synonyms	(2S)-1,2-Pyrrolidinedicarboxylic Acid 1-(Phenylmethyl) Ester; (S)-1,2-Pyrrolidinedicarboxylic Acid 1-(Phenylmethyl) Ester; (2S)-1,2-L-2-Pyrrolidinedicarboxylic Acid 1-Benzyl Ester; (2S)-1-Pyrrolidinedicarboxylic Acid 1-(Phenylmethyl) Ester; (2S)-1-(Benzyloxycarbonyl)pyrrolidine-2-carboxylic Acid
Long Term Storage Condition	Room temperature (20–25°C) in a dry place
Handling instruction	Sample COA

Test	Results
Appearance	White to off-white crystalline powder
Water content by KF/TGA	Sample COA
% Potency = [100 - (Water content by KF)] X HPLC Purity)] / 100	Sample COA
Identification by HNMR	Sample COA
Identification By IR	Sample COA
Mass (ESI)	Sample COA
Solubility
Purity	NLT 98%
Analysis Date (Release Date)	Sample COA
Attachments	Sample COA
Other Information	Sample COA
Note: This material can be used as a referance standard and is for research purpose ONLY and not for human consumption