PRODUCT NAME: Acalabrutinib Impurity 17
Date of Mfg: Sample COA	RETEST DATE: Sample COA

Catalogue Number	ATB-009
Lot Number	Sample COA
Batch Quantity	Sample COA
CAS Number	2412166-56-2
Mol. Formula	C30H25N7O3
Molecular Wt	531.6 g/mol
Long Term Storage Condition	2-8°C Refrigerator	Handling instruction	Sample COA
IUPAC	(S)-4-(9-(1-(But-2-ynoyl)pyrrolidin-2-yl)-2-methyl-4-oxo-4H-imidazo[5',1':3,4]pyrazino[1,2-a]pyrimidin-11-yl)-N-(pyridin-2-yl)benzamide
Chemical Name	Acalabrutinib Impurity 17
Synonyms	Benzamide, 4-[2-methyl-4-oxo-9-[(2S)-1-(1-oxo-2-butyn-1-yl)-2-pyrrolidinyl]-4H-imidazo[5′,1′:3,4]pyrazino[1,2-a]pyrimidin-11-yl]-N-2-pyridinyl; 4-[2-Methyl-4-oxo-9-[(2S)-1-(1-oxo-2-butyn-1-yl)-2-pyrrolidinyl]-4H-imidazo[5′,1′:3,4]pyrazino[1,2-a]pyrimidin-11-yl]-N-2-pyridinylbenzamide

Test	Results
Appearance	Pale yellow to off-white crystalline powder
Identification by 1H NMR	Sample COA
Identification By IR	Sample COA
Mass (ESI)	Sample COA
Purity	NLT 98%
Wt. Loss by TGA	Sample COA
% Potency	Sample COA
Solubility
QC Release Date	Sample COA
Attachments	Sample COA
Note: This material can be used as a referance standard and is for research purpose ONLY and not for human consumption