CERTIFICATE OF ANALYSIS

PRODUCT NAME: Bosentan USP Related Compound A
Date of Mfg: Sample COA RETEST DATE: Sample COA
Catalogue Number BOA-003
Item/Batch Number Sample COA
Quantity Sample COA
CAS Number 150727-06-3
Alternate CAS Number 1218951-79-1(cesium salt)
Mol. Formula C25H24ClN5O4S
Molecular Wt 526.0 g/mol
IUPAC (4-(Tert-butyl)-N-[6-chloro-5-(2-methoxyphenoxy)-(2,2'-bipyrimidin)-4-yl] benzenesulfonamide)
Synonyms Bosentan Monohydrate - Impurity A (EP/BP) (As per EP Monograph 37.3); N-[6-Chloro-5-(2-methoxyphenoxy)-(2,2-bipyrimidine)4-4-yl]-(1,1-dimethylethyl)-benzenesulfonamide; 4-tert-Butyl-N-[6-chloro-5-(2-methoxyphenoxy)-2-(2-pyrimidinyl)-4-pyrimidinyl]benzeneSulfonamide; Bosentan Related Compound A
Long Term Storage Condition 2-8°C Refrigerator
Handling instruction Sample COA
Test Results
Appearance white to off-white crystalline powder
Water content by KF/TGA Sample COA
% Potency = [100 - (Water content by KF)] X HPLC Purity)] / 100 Sample COA
Identification by HNMR Sample COA
Identification By IR Sample COA
Mass (ESI) Sample COA
Solubility
Purity NLT 98%
Analysis Date (Release Date) Sample COA
Attachments Sample COA
Other Information Sample COA
Note: This material can be used as a referance standard and is for research purpose ONLY and not for human consumption
This is Sample COA