PRODUCT NAME: Acalabrutinib Impurity 13
Date of Mfg: Sample COA	RETEST DATE: Sample COA

Catalogue Number	ATB-028
Item/Batch Number	Sample COA
Quantity	Sample COA
CAS Number	NA
Mol. Formula	C26H23N7O3
Molecular Wt	481.5 g/mol
IUPAC	(S)-2-(4-(8-Amino-3-(1-(but-2-ynoyl)pyrrolidin-2-yl)imidazo[1,5-a]pyrazin-1-yl)benzamido)pyridine 1-oxide
Synonyms	(S)-N-(1-Oxidopyridin-2-yl)-4-[8-amino-3-(1-but-2-ynoylpyrrolidin-2-yl)imidazo[1,5-a]pyrazin-1-yl]benzamide; PROTAC linker N-oxide variant VHL-003B
Long Term Storage Condition	6 months at -20°C
Handling instruction	Sample COA

Test	Results
Appearance	Bright yellow crystalline solid
Water content by KF/TGA	Sample COA
% Potency = [100 - (Water content by KF)] X HPLC Purity)] / 100	Sample COA
Identification by HNMR	Sample COA
Identification By IR	Sample COA
Mass (ESI)	Sample COA
Solubility
Purity	NLT 98%
Analysis Date (Release Date)	Sample COA
Attachments	Sample COA
Other Information	Sample COA
Note: This material can be used as a referance standard and is for research purpose ONLY and not for human consumption