PRODUCT NAME: Acalabrutinib Impurity 13
Date of Mfg: Sample COA	RETEST DATE: Sample COA

Catalogue Number	ATB-028
Lot Number	Sample COA
Batch Quantity	Sample COA
CAS Number	NA
Mol. Formula	C26H23N7O3
Molecular Wt	481.5 g/mol
Long Term Storage Condition	6 months at -20°C	Handling instruction	Sample COA
IUPAC	(S)-2-(4-(8-Amino-3-(1-(but-2-ynoyl)pyrrolidin-2-yl)imidazo[1,5-a]pyrazin-1-yl)benzamido)pyridine 1-oxide
Chemical Name	Acalabrutinib Impurity 13
Synonyms	(S)-N-(1-Oxidopyridin-2-yl)-4-[8-amino-3-(1-but-2-ynoylpyrrolidin-2-yl)imidazo[1,5-a]pyrazin-1-yl]benzamide; PROTAC linker N-oxide variant VHL-003B

Test	Results
Appearance	Bright yellow crystalline solid
Identification by 1H NMR	Sample COA
Identification By IR	Sample COA
Mass (ESI)	Sample COA
Purity	NLT 98%
Wt. Loss by TGA	Sample COA
% Potency	Sample COA
Solubility
QC Release Date	Sample COA
Attachments	Sample COA
Note: This material can be used as a referance standard and is for research purpose ONLY and not for human consumption