PRODUCT NAME: Acalabrutinib N-Nitroso Impurity 3
Date of Mfg: Sample COA	RETEST DATE: Sample COA

Catalogue Number	NIT-035
Item/Batch Number	Sample COA
Quantity	Sample COA
CAS Number	NA
Mol. Formula	C10H11BrN6O
Molecular Wt	311.1 g/mol
IUPAC	(S)-1-Bromo-3-(1-nitrosopyrrolidin-2-yl)imidazo[1,5-a]pyrazin-8-amine
Synonyms	Acalabrutinib Nitroso Impurity 3
Long Term Storage Condition	-20°C in dark (1 month)
Handling instruction	Sample COA

Test	Results
Appearance	Deep red crystalline solid
Water content by KF/TGA	Sample COA
% Potency = [100 - (Water content by KF)] X HPLC Purity)] / 100	Sample COA
Identification by HNMR	Sample COA
Identification By IR	Sample COA
Mass (ESI)	Sample COA
Solubility
Purity	NLT 98%
Analysis Date (Release Date)	Sample COA
Attachments	Sample COA
Other Information	Sample COA
Note: This material can be used as a referance standard and is for research purpose ONLY and not for human consumption