PRODUCT NAME: Acalabrutinib Impurity 14
Date of Mfg: Sample COA	RETEST DATE: Sample COA

Catalogue Number	ATB-029
Item/Batch Number	Sample COA
Quantity	Sample COA
CAS Number	NA
Mol. Formula	C47H42N12O3
Molecular Wt	822.9 g/mol
IUPAC	4-(8-Amino-3-((1R)-2-((S)-2-(8-amino-1-(4-(phenylcarbamoyl)phenyl)imidazo[1,5-a]pyrazin-3-yl)pyrrolidine-1-carbonyl)cyclopentyl)imidazo[1,5-a]pyrazin-
Synonyms	(1R,2S)-Cyclopentane-linked bis-imidazopyrazine PROTAC; EGFR/BRD4 bifunctional degrader V-0047X
Long Term Storage Condition	3 months at -20°C
Handling instruction	Sample COA

Test	Results
Appearance	Pale yellow-green crystalline solid
Water content by KF/TGA	Sample COA
% Potency = [100 - (Water content by KF)] X HPLC Purity)] / 100	Sample COA
Identification by HNMR	Sample COA
Identification By IR	Sample COA
Mass (ESI)	Sample COA
Solubility
Purity	NLT 98%
Analysis Date (Release Date)	Sample COA
Attachments	Sample COA
Other Information	Sample COA
Note: This material can be used as a referance standard and is for research purpose ONLY and not for human consumption