PRODUCT NAME: Nintedanib IHRS
Date of Mfg: Sample COA	RETEST DATE: Sample COA

Catalogue Number	NNT-015
Item/Batch Number	Sample COA
Quantity	Sample COA
CAS Number	656247-17-5
Alternate CAS Number	656247-18-6(Esylate Salt)
Mol. Formula	C₃₁H₃₃N₅O₄
Molecular Wt	539.62 g/mol
IUPAC	(3Z)-2,3-Dihydro-3-[[[4-[methyl[2-(4-methyl-1-piperazinyl)acetyl]amino]phenyl]amino]phenylmethylene]-2-oxo-H-Indole-6-carboxylic Acid Methyl Ester
Synonyms	Nintedanib; (3Z)-2,3-Dihydro-3-[[[4-[methyl[2-(4-methyl-1-piperazinyl)acetyl]amino]phenyl]amino]phenylmethylene]-2-oxo-H-Indole-6-carboxylic Acid Methyl Ester; Ofev; Vargatef; (Z)-Methyl 3-(((4-(N-methyl-2-(4-methylpiperazin-1-yl)acetamido)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate
Long Term Storage Condition	2-8°C Refrigerator
Handling instruction	Sample COA

Test	Results
Appearance	Light Green to Light Yellow Solid
Water content by KF/TGA	Sample COA
% Potency = [100 - (Water content by KF)] X HPLC Purity)] / 100	Sample COA
Identification by HNMR	Sample COA
Identification By IR	Sample COA
Mass (ESI)	Sample COA
Solubility
Purity	NLT 98%
Analysis Date (Release Date)	Sample COA
Attachments	Sample COA
Other Information	Sample COA
Note: This material can be used as a referance standard and is for research purpose ONLY and not for human consumption