CERTIFICATE OF ANALYSIS

PRODUCT NAME: Ibrutinib Dimer Impurity
Date of Mfg: Sample COA RETEST DATE: Sample COA
Catalogue Number IBR-001
Item/Batch Number Sample COA
Quantity Sample COA
CAS Number 2031255-23-7
Mol. Formula C₅₀H₄₈N₁₂O₄
Molecular Wt 880.99
Synonyms 1-((R)-3-(4-((3-((R)-3-(4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)-3-oxopropyl)amino)-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one
Long Term Storage Condition Amber Vial, Refrigerator, Under inert atmosphere
Handling instruction Sample COA
Test Results
Appearance White to Off-White Solid
Water content by KF/TGA Sample COA
% Potency = [100 - (Water content by KF)] X HPLC Purity)] / 100 Sample COA
Identification by HNMR Sample COA
Identification By IR Sample COA
Mass (ESI) Sample COA
Solubility Chloroform (Slightly), DMSO (Slightly)
Purity NLT 98%
Analysis Date (Release Date) Sample COA
Attachments Sample COA
Other Information Sample COA
Note: This material can be used as a referance standard and is for research purpose ONLY and not for human consumption
This is Sample COA