PRODUCT NAME: Acalabrutinib Amide Impurity
Date of Mfg: Sample COA	RETEST DATE: Sample COA

Catalogue Number	ATB-023
Item/Batch Number	Sample COA
Quantity	Sample COA
CAS Number	1420478-89-2
Mol. Formula	C30H27N7O3
Molecular Wt	533.58 g/mol
IUPAC	Benzyl (S)-2-(8-amino-1-(4-(pyridin-2-ylcarbamoyl)phenyl)imidazo[1,5-a]pyrazin-3-yl)pyrrolidine-1-carboxylate
Synonyms	(S)-1-CBz-2-[8-amino-1-(4-(2-pyridylcarbamoyl)phenyl)imidazo[1,5-a]pyrazin-3-yl]pyrrolidine; Benzyl (S)-2-[8-amino-1-(4-((pyridin-2-yl)carbamoyl)phenyl)imidazo[1,5-a]pyrazin-3-yl]-1-pyrrolidinecarboxylate
Long Term Storage Condition	2-8°C under nitrogen
Handling instruction	Sample COA

Test	Results
Appearance	Off-white to pale yellow crystalline solid
Water content by KF/TGA	Sample COA
% Potency = [100 - (Water content by KF)] X HPLC Purity)] / 100	Sample COA
Identification by HNMR	Sample COA
Identification By IR	Sample COA
Mass (ESI)	Sample COA
Solubility
Purity	NLT 98%
Analysis Date (Release Date)	Sample COA
Attachments	Sample COA
Other Information	Sample COA
Note: This material can be used as a referance standard and is for research purpose ONLY and not for human consumption