PRODUCT NAME: Acalabrutinib Amide Impurity
Date of Mfg: Sample COA	RETEST DATE: Sample COA

Catalogue Number	ATB-023
Lot Number	Sample COA
Batch Quantity	Sample COA
CAS Number	1420478-89-2
Mol. Formula	C30H27N7O3
Molecular Wt	533.58 g/mol
Long Term Storage Condition	2-8°C under nitrogen	Handling instruction	Sample COA
IUPAC	Benzyl (S)-2-(8-amino-1-(4-(pyridin-2-ylcarbamoyl)phenyl)imidazo[1,5-a]pyrazin-3-yl)pyrrolidine-1-carboxylate
Chemical Name	Acalabrutinib Amide Impurity
Synonyms	(S)-1-CBz-2-[8-amino-1-(4-(2-pyridylcarbamoyl)phenyl)imidazo[1,5-a]pyrazin-3-yl]pyrrolidine; Benzyl (S)-2-[8-amino-1-(4-((pyridin-2-yl)carbamoyl)phenyl)imidazo[1,5-a]pyrazin-3-yl]-1-pyrrolidinecarboxylate

Test	Results
Appearance	Off-white to pale yellow crystalline solid
Identification by 1H NMR	Sample COA
Identification By IR	Sample COA
Mass (ESI)	Sample COA
Purity	NLT 98%
Wt. Loss by TGA	Sample COA
% Potency	Sample COA
Solubility
QC Release Date	Sample COA
Attachments	Sample COA
Note: This material can be used as a referance standard and is for research purpose ONLY and not for human consumption