PRODUCT NAME: Acalabrutinib 8-Hydroxy Impurity
Date of Mfg: Sample COA	RETEST DATE: Sample COA

Catalogue Number	ATB-003
Item/Batch Number	Sample COA
Quantity	Sample COA
CAS Number	NA
Mol. Formula	C26H22N6O3
Molecular Wt	466.5 g/mol
IUPAC	(S)-4-(3-(1-(But-2-ynoyl)pyrrolidin-2-yl)-8-hydroxyimidazo[1,5-a]pyrazin-1-yl)-N-(pyridin-2-yl)benzamide
Synonyms	(S)-4-(3-(1-(But-2-ynoyl)pyrrolidin-2-yl)-8-hydroxyimidazo[1,5-a]pyrazin-1-yl)-N-(pyridin-2-yl)benzamide
Long Term Storage Condition	2-8°C Refrigerator
Handling instruction	Sample COA

Test	Results
Appearance	white to off-white crystalline powder
Water content by KF/TGA	Sample COA
% Potency = [100 - (Water content by KF)] X HPLC Purity)] / 100	Sample COA
Identification by HNMR	Sample COA
Identification By IR	Sample COA
Mass (ESI)	Sample COA
Solubility
Purity	NLT 98%
Analysis Date (Release Date)	Sample COA
Attachments	Sample COA
Other Information	Sample COA
Note: This material can be used as a referance standard and is for research purpose ONLY and not for human consumption