PRODUCT NAME: Afatinib Impurity 39
Date of Mfg: Sample COA	RETEST DATE: Sample COA

Catalogue Number	AFI-043
Item/Batch Number	Sample COA
Quantity	Sample COA
CAS Number	2223677-66-3
Mol. Formula	C22H21ClFN5O4
Molecular Wt	473.9 g/mol
IUPAC	(S)-N1-(4-((3-chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-N2,N2-dimethyloxalamide
Synonyms	Ethanediamide, N2-[4-[(3-chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-N1,N1-dimethyl; N2-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-N1,N1-dimethylethanediamide
Long Term Storage Condition	2-8°C Refrigerator
Handling instruction	Sample COA

Test	Results
Appearance	white to off-white solid powder
Water content by KF/TGA	Sample COA
% Potency = [100 - (Water content by KF)] X HPLC Purity)] / 100	Sample COA
Identification by HNMR	Sample COA
Identification By IR	Sample COA
Mass (ESI)	Sample COA
Solubility
Purity	NLT 98%
Analysis Date (Release Date)	Sample COA
Attachments	Sample COA
Other Information	Sample COA
Note: This material can be used as a referance standard and is for research purpose ONLY and not for human consumption