PRODUCT NAME: Acalabrutinib Impurity 27
Date of Mfg: Sample COA	RETEST DATE: Sample COA

Catalogue Number	ATB-013
Lot Number	Sample COA
Batch Quantity	Sample COA
CAS Number	1420478-88-1
Mol. Formula	C18H18BrN5O2
Molecular Wt	416.3 g/mol
Long Term Storage Condition	2-8°C Refrigerator	Handling instruction	Sample COA
IUPAC	Benzyl (S)-2-(8-amino-1-bromoimidazo[1,5-a]pyrazin-3-yl)pyrrolidine-1-carboxylate
Chemical Name	Acalabrutinib Impurity 27
Synonyms	1-Pyrrolidinecarboxylic acid, 2-(8-amino-1-bromoimidazo[1,5-a]pyrazin-3-yl)-, phenylmethyl ester, (2S); Phenylmethyl (2S)-2-(8-amino-1-bromoimidazo[1,5-a]pyrazin-3-yl)-1-pyrrolidinecarboxylate; (S)-Benzyl 2-(8-amino-1-bromoimidazo[1,5-a]pyrazin-3-yl)pyrrolidine-1-carboxylate

Test	Results
Appearance	Off-white to pale yellow crystalline powder
Identification by 1H NMR	Sample COA
Identification By IR	Sample COA
Mass (ESI)	Sample COA
Purity	NLT 98%
Wt. Loss by TGA	Sample COA
% Potency	Sample COA
Solubility
QC Release Date	Sample COA
Attachments	Sample COA
Note: This material can be used as a referance standard and is for research purpose ONLY and not for human consumption