CERTIFICATE OF ANALYSIS

PRODUCT NAME: Afatinib D6
Date of Mfg: Sample COA RETEST DATE: Sample COA
Catalogue Number AFI-063
Item/Batch Number Sample COA
Quantity Sample COA
CAS Number 1313874-96-2
Mol. Formula C24H19D6ClFN5O3
Molecular Wt 492.0 g/mol
IUPAC (S,E)-4-(Bis(methyl-d3)amino)-N-(4-((3-chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)but-2-enamide
Synonyms (2E)-N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-2-butenamide-d6; BIBW 2992-d6
Long Term Storage Condition -20°C
Handling instruction Sample COA
Test Results
Appearance white to off-white solid
Water content by KF/TGA Sample COA
% Potency = [100 - (Water content by KF)] X HPLC Purity)] / 100 Sample COA
Identification by HNMR Sample COA
Identification By IR Sample COA
Mass (ESI) Sample COA
Solubility
Purity NLT 98%
Analysis Date (Release Date) Sample COA
Attachments Sample COA
Other Information Sample COA
Note: This material can be used as a referance standard and is for research purpose ONLY and not for human consumption
This is Sample COA