PRODUCT NAME: N-Nitroso Lorlatinib Impurity 1
Date of Mfg: Sample COA	RETEST DATE: Sample COA

Catalogue Number	NIO-338
Item/Batch Number	Sample COA
Quantity	Sample COA
CAS Number	NA
Mol. Formula	C43H36F2N14O6
Molecular Wt	882.8
Synonyms	N-((R)-15-cyano-55-fluoro-11,4,7-trimethyl-6-oxo-11H-3-oxa-7-aza-2(2,4)-pyridina-1(4,3)-pyrazola-5(1,2)-benzenacyclooctaphane-26-yl)-N-((((R)-15-cyano-55-fluoro-11,4,7-trimethyl-6-oxo-11H-3-oxa-7-aza-2(3,5)-pyridina-1(4,3)-pyrazola-5(1,2)-benzenacyclooctaphane-26-yl)(nitroso)amino)methyl)nitrous amide
Long Term Storage Condition	Keep container tightly closed in a dry and well-ventilated place
Handling instruction	Sample COA

Test	Results
Appearance
Water content by KF/TGA	Sample COA
% Potency = [100 - (Water content by KF)] X HPLC Purity)] / 100	Sample COA
Identification by HNMR	Sample COA
Identification By IR	Sample COA
Mass (ESI)	Sample COA
Solubility
Purity	NLT 98%
Analysis Date (Release Date)	Sample COA
Attachments	Sample COA
Other Information	Sample COA
Note: This material can be used as a referance standard and is for research purpose ONLY and not for human consumption