PRODUCT NAME: N-Nitroso Lorlatinib Impurity 2
Date of Mfg: Sample COA	RETEST DATE: Sample COA

Catalogue Number	NIO-337
Lot Number	Sample COA
Batch Quantity	Sample COA
CAS Number	NA
Mol. Formula	C43H37F2N13O5
Molecular Wt	853.9
Long Term Storage Condition	Keep container tightly closed in a dry and well-ventilated place	Handling instruction	Sample COA
Chemical Name	N-Nitroso Lorlatinib Impurity 2
Synonyms	N-((((R)-15-cyano-55-fluoro-11,4,7-trimethyl-6-oxo-11H-3-oxa-7-aza-2(2,4)-pyridina-1(4,3)-pyrazola-5(1,2)-benzenacyclooctaphane-26-yl)amino)methyl)-N-((R)-15-cyano-55-fluoro-11,4,7-trimethyl-6-oxo-11H-3-oxa-7-aza-2(3,5)-pyridina-1(4,3)-pyrazola-5(1,2)-benzenacyclooctaphane-26-yl)nitrous amide

Test	Results
Appearance
Identification by 1H NMR	Sample COA
Identification By IR	Sample COA
Mass (ESI)	Sample COA
Purity	NLT 98%
Wt. Loss by TGA	Sample COA
% Potency	Sample COA
Solubility
QC Release Date	Sample COA
Attachments	Sample COA
Note: This material can be used as a referance standard and is for research purpose ONLY and not for human consumption