PRODUCT NAME: Acalabrutinib Impurity 33
Date of Mfg: Sample COA	RETEST DATE: Sample COA

Catalogue Number	ATB-043
Lot Number	Sample COA
Batch Quantity	Sample COA
CAS Number	2230757-49-8
Mol. Formula	C22H19N7O
Molecular Wt	397.4 g/mol
Long Term Storage Condition	2-8°C under nitrogen	Handling instruction	Sample COA
IUPAC	4-(8-Amino-3-(3,4-dihydro-2H-pyrrol-5-yl)imidazo[1,5-a]pyrazin-1-yl)-N-(pyridin-2-yl)benzamide
Chemical Name	Acalabrutinib Impurity 33
Synonyms	Benzamide, 4-[8-amino-3-(3,4-dihydro-2H-pyrrol-5-yl)imidazo[1,5-a]pyrazin-1-yl]-N-2-pyridinyl

Test	Results
Appearance	Pale yellow to beige crystalline solid
Identification by 1H NMR	Sample COA
Identification By IR	Sample COA
Mass (ESI)	Sample COA
Purity	NLT 98%
Wt. Loss by TGA	Sample COA
% Potency	Sample COA
Solubility
QC Release Date	Sample COA
Attachments	Sample COA
Note: This material can be used as a referance standard and is for research purpose ONLY and not for human consumption