CERTIFICATE OF ANALYSIS

PRODUCT NAME: Afatinib Impurity 26
Date of Mfg: Sample COA RETEST DATE: Sample COA
Catalogue Number AFI-035
Item/Batch Number Sample COA
Quantity Sample COA
CAS Number 314771-88-5
Mol. Formula C18H14ClFN4O4
Molecular Wt 404.8 g/mol
IUPAC (S)-N-(3-Chloro-4-fluorophenyl)-6-nitro-7-((tetrahydrofuran-3-yl)oxy)quinazolin-4-amine
Synonyms ((Tetrahydrofuran-3-yl)oxy)quinazolin-4-amine, (S)-N-(3-chloro-4-fluorophenyl)-6-nitro-7-
Long Term Storage Condition 2-8°C Refrigerator
Handling instruction Sample COA
Test Results
Appearance yellow to light brown solid powder
Water content by KF/TGA Sample COA
% Potency = [100 - (Water content by KF)] X HPLC Purity)] / 100 Sample COA
Identification by HNMR Sample COA
Identification By IR Sample COA
Mass (ESI) Sample COA
Solubility
Purity NLT 98%
Analysis Date (Release Date) Sample COA
Attachments Sample COA
Other Information Sample COA
Note: This material can be used as a referance standard and is for research purpose ONLY and not for human consumption
This is Sample COA