CERTIFICATE OF ANALYSIS

PRODUCT NAME: Adagrasib Impurity 11
Date of Mfg: Sample COA RETEST DATE: Sample COA
Catalogue Number ADG-013
Item/Batch Number Sample COA
Quantity Sample COA
CAS Number 791828-58-5
Mol. Formula C21H28N4O5
Molecular Wt 416.5 g/mol
IUPAC methyl (6S,7S)-7-(hydroxycarbamoyl)-6-(4-phenylpiperazine-1-carbonyl)-5-azaspiro[2.5]octane-5-carboxylate
Synonyms methyl (6S,7S)-7-(hydroxycarbamoyl)-6-(4-phenylpiperazine-1-carbonyl)-5-azaspiro[2.5]octane-5-carboxylate
Long Term Storage Condition -20°C under argon (hygroscopic and light-sensitive)
Handling instruction Sample COA
Test Results
Appearance White to off-white crystalline powder
Water content by KF/TGA Sample COA
% Potency = [100 - (Water content by KF)] X HPLC Purity)] / 100 Sample COA
Identification by HNMR Sample COA
Identification By IR Sample COA
Mass (ESI) Sample COA
Solubility
Purity NLT 98%
Analysis Date (Release Date) Sample COA
Attachments Sample COA
Other Information Sample COA
Note: This material can be used as a referance standard and is for research purpose ONLY and not for human consumption
This is Sample COA