PRODUCT NAME: Acalabrutinib Diamide Impurity
Date of Mfg: Sample COA	RETEST DATE: Sample COA

Catalogue Number	ATB-022
Lot Number	Sample COA
Batch Quantity	Sample COA
CAS Number	NA
Mol. Formula	C30H25N7O3
Molecular Wt	531.56 g/mol
Long Term Storage Condition	-20°C (desiccant required)	Handling instruction	Sample COA
IUPAC	(R)-4-(8-propiolamido-3-(1-propioloylpyrrolidin-2-yl)imidazo[1,5-a]pyrazin-1-yl)-N-(pyridin-2-yl)benzamide
Chemical Name	Acalabrutinib Diamide Impurity
Synonyms	(R)-N-(2-Pyridyl)-4-[8-propynamido-3-(1-propynoyl-2-pyrrolidinyl)imidazo[1,5-a]pyrazin-1-yl]benzamide; (R)-1-(2-Pyridinylcarbamoyl)-4-[8-propiolamido-3-(1-propioloyl-L-prolyl)imidazo[1,5-a]pyrazin-1-yl]benzene

Test	Results
Appearance	Pale yellow to light brown amorphous solid
Identification by 1H NMR	Sample COA
Identification By IR	Sample COA
Mass (ESI)	Sample COA
Purity	NLT 98%
Wt. Loss by TGA	Sample COA
% Potency	Sample COA
Solubility
QC Release Date	Sample COA
Attachments	Sample COA
Note: This material can be used as a referance standard and is for research purpose ONLY and not for human consumption