PRODUCT NAME: Afatinib Impurity 13
Date of Mfg: Sample COA	RETEST DATE: Sample COA

Catalogue Number	AFI-003
Item/Batch Number	Sample COA
Quantity	Sample COA
CAS Number	2413212-19-6
Mol. Formula	C22H20ClFN4O4
Molecular Wt	458.9 g/mol
IUPAC	1-(4-((3-Chloro-4-fluorophenyl)amino)-7-(((R)-tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-5-hydroxypyrrolidin-2-one
Synonyms	2-Pyrrolidinone, 1-[4-[(3-chloro-4-fluorophenyl)amino]-7-[[(3R)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-5-hydroxy-; 1-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[[(3R)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-5-hydroxy-2-pyrrolidinone
Long Term Storage Condition	2-8°C in desiccator
Handling instruction	Sample COA

Test	Results
Appearance	Off-white to pale yellow crystalline powder
Water content by KF/TGA	Sample COA
% Potency = [100 - (Water content by KF)] X HPLC Purity)] / 100	Sample COA
Identification by HNMR	Sample COA
Identification By IR	Sample COA
Mass (ESI)	Sample COA
Solubility
Purity	NLT 98%
Analysis Date (Release Date)	Sample COA
Attachments	Sample COA
Other Information	Sample COA
Note: This material can be used as a referance standard and is for research purpose ONLY and not for human consumption