PRODUCT NAME: Amikacin Impurity 1
Date of Mfg: Sample COA	RETEST DATE: Sample COA

Catalogue Number	AMK-015
Lot Number	Sample COA
Batch Quantity	Sample COA
CAS Number	50866-72-3
Mol. Formula	C22H43N5O13
Molecular Wt	585.6 g/mol
Long Term Storage Condition	2-8°C Refrigerator	Handling instruction	Sample COA
IUPAC	(S)-4-amino-N-(((2R,3S,4S,5R,6R)-6-(((1R,2R,3S,4R,6S)-4,6-diamino-3-(((2S,3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl
Chemical Name	Amikacin Impurity 1
Synonyms	Amikacin Sulfate Impurity E (As per 35.1 EP Monograph); 6-O-(6-amino-6-deoxy-a-D-glucopyranosyl)-4-O-[5-[[(2S)-4-amino-2-hydroxybutanoyl]amino]-3-deoxy-a-Dglucopyranosyl]-2-deoxy-D-streptamine; (S)-4-Amino-N-(((2R,3S,4S,5R,6R)-6-(((1R,2R,3S,4R,6S)-4,6-diamino-3-(((2S,3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-2-hydroxycyclohexyl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)methyl)-2-hydroxybutanamide

Test	Results
Appearance	white or off-white, crystalline powder
Identification by 1H NMR	Sample COA
Identification By IR	Sample COA
Mass (ESI)	Sample COA
Purity	NLT 98%
Wt. Loss by TGA	Sample COA
% Potency	Sample COA
Solubility
QC Release Date	Sample COA
Attachments	Sample COA
Note: This material can be used as a referance standard and is for research purpose ONLY and not for human consumption