PRODUCT NAME: Acalabrutinib R-Isomer
Date of Mfg: Sample COA	RETEST DATE: Sample COA

Catalogue Number	ATB-016
Lot Number	Sample COA
Batch Quantity	Sample COA
CAS Number	1952316-43-6
Mol. Formula	C₂₆H₂₃N₇O₂
Molecular Wt	465.51 g/mol
Long Term Storage Condition	2-8°C Refrigerator	Handling instruction	Sample COA
IUPAC	(R)-4-(8-Amino-3-(1-(but-2-ynoyl)pyrrolidin-2-yl)imidazo[1,5-a]pyrazin-1-yl)-N-(pyridin-2-yl)benzamide
Chemical Name	Acalabrutinib R-Isomer
Synonyms	(R)-4-(8-Amino-3-(1-(but-2-ynoyl)pyrrolidin-2-yl)imidazo[1,5-a]pyrazin-1-yl)-N-(pyridin-2-yl)benzamide; Benzamide, 4-[8-amino-3-[(2R)-1-(1-oxo-2-butyn-1-yl)-2-pyrrolidinyl]imidazo[1,5-a]pyrazin-1-yl]-N-2-pyridinyl; 4-[8-Amino-3-[(2R)-1-(1-oxo-2-butyn-1-yl)-2-pyrrolidinyl]imidazo[1,5-a]pyrazin-1-yl]-N-2-pyridinylbenzamide

Test	Results
Appearance	Off-white to pale yellow solid powder
Identification by 1H NMR	Sample COA
Identification By IR	Sample COA
Mass (ESI)	Sample COA
Purity	NLT 98%
Wt. Loss by TGA	Sample COA
% Potency	Sample COA
Solubility
QC Release Date	Sample COA
Attachments	Sample COA
Note: This material can be used as a referance standard and is for research purpose ONLY and not for human consumption