PRODUCT NAME: Acalabrutinib Impurity 21
Date of Mfg: Sample COA	RETEST DATE: Sample COA

Catalogue Number	ATB-011
Item/Batch Number	Sample COA
Quantity	Sample COA
CAS Number	1418307-18-2
Mol. Formula	C18H17ClN4O2
Molecular Wt	356.8 g/mol
IUPAC	Benzyl (S)-2-(8-chloroimidazo[1,5-a]pyrazin-3-yl)pyrrolidine-1-carboxylate
Synonyms	1-Pyrrolidinecarboxylic acid, 2-(8-chloroimidazo[1,5-a]pyrazin-3-yl)-, phenylmethyl ester, (2S); (S)-Benzyl 2-(8-chloroimidazo[1,5-a]pyrazin-3-yl)pyrrolidine-1-carboxylate
Long Term Storage Condition	40°C/75% RH
Handling instruction	Sample COA

Test	Results
Appearance	White to off-white crystalline powder
Water content by KF/TGA	Sample COA
% Potency = [100 - (Water content by KF)] X HPLC Purity)] / 100	Sample COA
Identification by HNMR	Sample COA
Identification By IR	Sample COA
Mass (ESI)	Sample COA
Solubility
Purity	NLT 98%
Analysis Date (Release Date)	Sample COA
Attachments	Sample COA
Other Information	Sample COA
Note: This material can be used as a referance standard and is for research purpose ONLY and not for human consumption