PRODUCT NAME: Afatinib N-Nitroso Impurity 2
Date of Mfg: Sample COA	RETEST DATE: Sample COA

Catalogue Number	NIT-068
Item/Batch Number	Sample COA
Quantity	Sample COA
CAS Number	NA
Mol. Formula	C23H22ClFN6O4
Molecular Wt	500.9 g/mol
IUPAC	(S,E)-N-(4-((3-chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(methyl(nitroso)amino)but-2-enamide
Synonyms	(S,E)-N-(4-((3-chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(methyl(nitroso)amino)but-2-enamide
Long Term Storage Condition	–20°C or 4°C
Handling instruction	Sample COA

Test	Results
Appearance	solid (powder or crystalline form)
Water content by KF/TGA	Sample COA
% Potency = [100 - (Water content by KF)] X HPLC Purity)] / 100	Sample COA
Identification by HNMR	Sample COA
Identification By IR	Sample COA
Mass (ESI)	Sample COA
Solubility
Purity	NLT 98%
Analysis Date (Release Date)	Sample COA
Attachments	Sample COA
Other Information	Sample COA
Note: This material can be used as a referance standard and is for research purpose ONLY and not for human consumption