CERTIFICATE OF ANALYSIS

PRODUCT NAME: Adagrasib N-Nitroso Impurity 2
Date of Mfg: Sample COA RETEST DATE: Sample COA
Catalogue Number NIT-048
Item/Batch Number Sample COA
Quantity Sample COA
CAS Number NA
Mol. Formula C30H40N8O4
Molecular Wt 576.69 g/mol
IUPAC Tert-butyl(S)-4-(7-benzyl-2-(((S)-1-nitrosopyrrolidin-2-yl)methoxy)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-4-yl)-2-(cyanomethyl)piperazine-1-carboxy
Synonyms (S)-tert-butyl4-(7-benzyl-2-(((S)-1-nitrosopyrrolidin-2-yl)methoxy)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-4-yl)-2-(cyanomethyl)piperazine-1-carboxylate
Long Term Storage Condition -20°C in anhydrous DMSO (1 month)
Handling instruction Sample COA
Test Results
Appearance Yellow to orange viscous oil (may solidify at <0°C)
Water content by KF/TGA Sample COA
% Potency = [100 - (Water content by KF)] X HPLC Purity)] / 100 Sample COA
Identification by HNMR Sample COA
Identification By IR Sample COA
Mass (ESI) Sample COA
Solubility
Purity NLT 98%
Analysis Date (Release Date) Sample COA
Attachments Sample COA
Other Information Sample COA
Note: This material can be used as a referance standard and is for research purpose ONLY and not for human consumption
This is Sample COA