PRODUCT NAME: Macitentan Pyrimidine Amine Impurity
Date of Mfg: Sample COA	RETEST DATE: Sample COA

Catalogue Number	MAC-003
Item/Batch Number	Sample COA
Quantity	Sample COA
CAS Number	1393813-42-7
Mol. Formula	C13H14BrClN4O2S
Molecular Wt	405.70 g/mol
IUPAC	5-(4-bromophenyl)-6-chloro-N-(propylsulfamoyl)pyrimidin-4-amine
Synonyms	Sulfamide,N-[5-(4-bromophenyl)-6-chloro-4-pyrimidinyl]-N`-propyl
Long Term Storage Condition	store at 2-8°C
Handling instruction	Sample COA

Test	Results
Appearance	Pale yellow solid
Water content by KF/TGA	Sample COA
% Potency = [100 - (Water content by KF)] X HPLC Purity)] / 100	Sample COA
Identification by HNMR	Sample COA
Identification By IR	Sample COA
Mass (ESI)	Sample COA
Solubility	methanol,DMSO
Purity	98%
Analysis Date (Release Date)	Sample COA
Attachments	Sample COA
Other Information	Sample COA
Note: This material can be used as a referance standard and is for research purpose ONLY and not for human consumption