PRODUCT NAME: Abemaciclib N-Nitroso Impurity 6
Date of Mfg: Sample COA	RETEST DATE: Sample COA

Catalogue Number	NIT-021
Item/Batch Number	Sample COA
Quantity	Sample COA
CAS Number	NA
Mol. Formula	C24H24F2N10O2
Molecular Wt	522.5 g/mol
IUPAC	N-(5-((4-Ethylpiperazin-1-yl)methyl)pyridin-2-yl)-N-(5-fluoro-4-(4-fluoro-2-methyl-1-nitroso-1H-benzo[d]imidazol-6-yl)pyrimidin-2-yl)nitrous amide
Synonyms	Abemaciclib Nitroso Impurity 6
Long Term Storage Condition	-20°C in argon-filled vial
Handling instruction	Sample COA

Test	Results
Appearance	Dark red to violet crystalline solid
Water content by KF/TGA	Sample COA
% Potency = [100 - (Water content by KF)] X HPLC Purity)] / 100	Sample COA
Identification by HNMR	Sample COA
Identification By IR	Sample COA
Mass (ESI)	Sample COA
Solubility
Purity	NLT 98%
Analysis Date (Release Date)	Sample COA
Attachments	Sample COA
Other Information	Sample COA
Note: This material can be used as a referance standard and is for research purpose ONLY and not for human consumption